49 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28002667	51	Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe.	Glaxosmithkline
27994766	28	Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.	University of Dundee
27682507	167	Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300.	Genentech
26701186	50	KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases.	University of Freiburg
26731131	2	Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.	University of Oxford
26230603	176	Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors.	Glaxosmithkline
25730130	20	A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach.	Universit£
25249180	146	The discovery of I-BET726 (GSK1324726A), a potent tetrahydroquinoline ApoA1 up-regulator and selective BET bromodomain inhibitor.	Glaxosmithkline
24345448	4	Azide-alkyne cycloaddition affording enzymatically tunable bisubstrate based inhibitors of histone acetyltransferase PCAF.	Utrecht University
24144283	100	Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains.	Icahn School of Medicine At Mount Sinai
22924434	4	Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions.	University of Oxford
19114310	30	Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60.	Georgia State University
19101154	28	Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs).	The Institute of Cancer Research
22100137	6	6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site.	University of Groningen
21353783	37	Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors.	Albert-Ludwigs-University of Freiburg
20655754	2	Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative.	Groningen Research Institute of Pharmacy
19683843	16	Reactivity of isothiazolones and isothiazolone-1-oxides in the inhibition of the PCAF histone acetyltransferase.	University of Groningen
19111471	19	Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones.	University of Groningen
27757418	27	Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.	University of Oxford
32410449	88	Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.	Glaxosmithkline R&D
32453591	70	Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.	University of Illinois At Chicago
31195169	46	Histone acetyltransferase inhibitors: An overview in synthesis, structure-activity relationship and molecular mechanism.	Sichuan University
30998845	58	Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.	Sichuan University
32314924	44	Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP.	Avera Institute For Human Genetics
30606676	83	Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.	Gilead Sciences
31910017	43	Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors.	Chinese Academy of Sciences
30297119	24	Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors.	Chinese Academy of Sciences
29656650	151	Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain.	University of Strathclyde
29169673	115	Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300.	Wuxi Apptec
28463487	185	Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor.	University of Michigan
30015487	96	Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor.	TBA
29448139	117	Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer.	Guangzhou Medical University
28527406	61	The relevance of K	University of Groningen
28892380	93	GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).	Genentech
28068087	80	Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies.	University College London
28268136	130	Methylpyrrole inhibitors of BET bromodomains.	Abbvie
28949521	88	Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor.	Abbvie